Volume 4, Number 2 (May 1998) Reviews  Targeting gene therapy vectors to CNS malignancies Spear MA, Herrlinger U, Rainov N, Pechan P, Weissleder R, Breakefield XO. pp. 133-147 (PDF) The class III variant of the epidermal growth factor receptor (EGFRvIII): characterization and utilization as an immunotherapeutic target Wikstrand CJ, Reist CJ, Archer GE, Zalutsky MR, Bigner DD. pp. 148-158 (PDF) Transgenic mice as research tools in neurocarcinogenesis Rovigatti U, Afanasyeva T, Brandner S, Hainfellner JA, Kiess M, Maddalena A, Malin G, Rulicke T, Steinbach J, Weissenberger J, Aguzzi A. pp. 159-174 (PDF) Tumor pathogenesis of human neurotropic JC virus in the CNS Gallia GL, Gordon J, Khalili K. pp. 175-181 (PDF) Papers  Sequence analyses of human tumor-associated SV40 DNAs and SV40 viral isolates from monkeys and humans Stewart AR, Lednicky JA, Butel JS. pp. 182-193 (PDF) Immune parameters affecting adenoviral vector gene therapy in the brain Parr MJ, Wen PY, Schaub M, Khoury SJ, Sayegh MH, Fine HA. pp. 194-203 (PDF) Principles of treatment of malignant gliomas in adults: an overview Azizi SA, Miyamoto C. pp. 204-216 (PDF) Differentially expressed gene products in glioblastoma cells suppressed for tumorigenicity Ligon AH, Pershouse MA, Jasser S, Hong YK, Yung WK, Steck PA. pp. 217-226 (PDF) Management of malignant glioma: role of surgery in relation to multimodality therapy Black P. pp. 227-236 (PDF) Short Communications  Effects on brain tumor cell proliferation by an adenovirus vector that bears the interleukin-4 gene Wei MX, Li F, Ono Y, Gauldie J, Chiocca EA. pp. 237-241 (PDF) Case Report  PCR detection of JC virus DNA in the brain tissue of a 9-year-old child with pleomorphic xanthoastrocytoma Boldorini R, Caldarelli-Stefano R, Monga G, Zocchi M, Mediati M, Tosoni A, Ferrante P. pp. 242-245 (PDF)